Facile synthesis of a CuSe/PVP nanocomposite for ultrasensitive non-enzymatic glucose biosensing
Momna Rasheed, Farhat Saira, Zahida Batool, Hasan M. Khan, Junaid Yaseen, Muhammad Arshad, Ambreen Kalsoom, Hafiz Ejaz Ahmed, Muhammad Naeem Ashiq
Abstract
with an LOD of 0.223 μM. Chronoamperometry measurements revealed a selective behavior of CuSe/PVP for glucose biosensing amongst ascorbic acid and dopamine as common interfering molecules. The nanocomposite was stable after 8 repeated cycles with 92% retention for glucose sensing capacity. This is attributed to the stable nature of the CuSe/PVP nanocomposite as well as higher surface area of available active sites. Herein the CuSe/PVP nanocomposite offered reasonable selectivity, high sensitivity wide linear range with very low LOD, as well as being abundant in nature, this Cu based biosensor has promising applications for future point of care tests (POCT).