Ni(I)–Alkyl Complexes Bearing Phenanthroline Ligands: Experimental Evidence for CO <sub>2</sub> Insertion at Ni(I) Centers
Rosie J. Somerville, Carlota Odena, Marc Obst, Nilay Hazari, Kathrin H. Hopmann, Rubén Martı́n
Abstract
Although the catalytic carboxylation of unactivated alkyl electrophiles has reached remarkable levels of sophistication, the intermediacy of (phenanthroline)Ni(I)–alkyl species—complexes proposed in numerous Ni-catalyzed reductive cross-coupling reactions—has been subject to speculation. Herein we report the synthesis of such elusive (phenanthroline)Ni(I) species and their reactivity with CO2, allowing us to address a long-standing question related to Ni-catalyzed carboxylation reactions.
Topics & Concepts
ChemistryAlkylCarboxylationElectrophilePhenanthrolineMigratory insertionReactivity (psychology)CatalysisMedicinal chemistryStereochemistryCombinatorial chemistryOrganic chemistryAlternative medicinePathologyMedicineCarbon dioxide utilization in catalysisCO2 Reduction Techniques and CatalystsCatalytic Cross-Coupling Reactions