Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

Jian Liu, Deodial Guiadeen, A. D. Krikorian, Xiaolei Gao, James Wang, Sobhana Babu Boga, Abdul‐Basit Alhassan, Wensheng Yu, Oleg Selyutin, Younong Yu, Rajan Anand, Jiayi Xu, Joseph Kelly, Joseph Duffy, Shilan Liu, Chundao Yang, Hao Wu, Jiaqiang Cai, Chad Bennett, Kevin M. Maloney, Sriram Tyagarajan, Ying‐Duo Gao, Thierry Fischmann, Jeremy Presland, My Sam Mansueto, Zangwei Xu, Erica Leccese, Jie Zhang-Hoover, Ian Knemeyer, Charles G. Garlisi, Peter Stivers, Philip E. Brandish, Alexandra Hicks, Ronald Kim, Joseph A. Kozlowski