Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives
Teresa Glomb, Piotr Świątek
Abstract
The worldwide development of antimicrobial resistance forces scientists to search for new compounds to which microbes would be sensitive. Many new structures contain the 1,3,4-oxadiazole ring, which have shown various antimicrobial activity, e.g., antibacterial, antitubercular, antifungal, antiprotozoal and antiviral. In many publications, the activity of new compounds exceeds the activity of already known antibiotics and other antimicrobial agents, so their potential as new drugs is very promising. The review of active antimicrobial 1,3,4-oxadiazole derivatives is based on the literature from 2015 to 2021.
Topics & Concepts
AntimicrobialAntiprotozoalOxadiazoleAntifungalAntibiotic resistanceChemistryAntibioticsCombinatorial chemistryMicrobiologyBiologyBiochemistryOrganic chemistryIn vitroSynthesis and biological activitySynthesis and Biological EvaluationClick Chemistry and Applications