Litcius/Paper detail

A bispecific antibody targeting HER2 and CLDN18.2 eliminates gastric cancer cells expressing dual antigens by enhancing the immune effector function

Jingying Yue, Shuai Shao, Jie Zhou, Wenting Luo, XU Yan-ling, Qinbin Zhang, Jing Jiang, Marie M. Zhu

2024Investigational New Drugs10 citationsDOI

Topics & Concepts

Antibody-dependent cell-mediated cytotoxicityTrastuzumabMonoclonal antibodyCytotoxicityCancer researchAntibodyCancerImmune systemMedicineAntigenImmunologyChemistryIn vitroBreast cancerInternal medicineBiochemistryHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins Research
A bispecific antibody targeting HER2 and CLDN18.2 eliminates gastric cancer cells expressing dual antigens by enhancing the immune effector function | Litcius