TSC2 regulates tumor susceptibility to TRAIL‐mediated T‐cell killing by orchestrating mTOR signaling
Chun‐Pu Lin, Joleen J.H. Traets, David W. Vredevoogd, Nils L. Visser, Daniel S. Peeper
Topics & Concepts
mTORC1PI3K/AKT/mTOR pathwayCancer researchImmune checkpointBiologyCTL*Immune systemmTORC2Cytotoxic T cellSignal transductionImmunologyImmunotherapyCell biologyCD8In vitroBiochemistryPI3K/AKT/mTOR signaling in cancerPolyomavirus and related diseasesCancer Mechanisms and Therapy