Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
Jianjian Zhu, Rashmi Patel, Anna Trofka, Brian D. Harfe, Susan Mackem
Topics & Concepts
MorphogenSonic hedgehogBiologyPatchedLimb developmentNumerical digitHedgehogCell biologyNeuroscienceAnatomyGeneticsSignal transductionGeneArithmeticMathematicsHedgehog Signaling Pathway StudiesCongenital limb and hand anomaliesDevelopmental Biology and Gene Regulation