A novel ionizable lipid with comprehensive improvements in transfection potency, immune profile and safety of lipid nanoparticle
Kundian Guo, Lingling Bu, Jintong Du, Wei Zhang, Jiayuan Xia, Mengmeng Tao, Xianyu Shao, Li-Jing Liu, Weijun Zhao, Yunsong Cai, Yong Yang, Xuben Hou, Ang Lin
Topics & Concepts
ReactogenicityImmunogenicityChemistrySquaramideGene deliveryBiophysicsTransfectionImmune systemBiochemistryBiologyImmunologyGeneCatalysisEnantioselective synthesisOrganocatalysisRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesViral Infections and Immunology Research