Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy
Menghao Shi, Jiulong Zhang, Yu Wang, Yanyan Han, Xiuli Zhao, Haiyang Hu, Mingxi Qiao, Dawei Chen
Topics & Concepts
Immunogenic cell deathImmunogenicityImmunotherapyCancer researchTumor microenvironmentImmune systemCancer immunotherapyMaterials scienceIndoleamine 2,3-dioxygenaseChemistryMedicineImmunologyBiochemistryTryptophanAmino acidNanoplatforms for cancer theranosticsCancer Immunotherapy and BiomarkersCancer, Stress, Anesthesia, and Immune Response