Secretory autophagy-induced bladder tumour-derived extracellular vesicle secretion promotes angiogenesis by activating the TPX2-mediated phosphorylation of the AURKA-PI3K-AKT axis
Xinyuan Li, Zongjie Wei, Haitao Yu, Yingjie Xu, Weiyang He, Xiang Zhou, Xin Gou
Topics & Concepts
AutophagyAngiogenesisProtein kinase BPI3K/AKT/mTOR pathwayCancer researchSecretionTumor microenvironmentDownregulation and upregulationBiologyCathepsin BPhosphorylationCell biologySignal transductionEndocrinologyApoptosisBiochemistryEnzymeTumor cellsGeneExtracellular vesicles in diseaseFerroptosis and cancer prognosisCancer-related molecular mechanisms research