Dietary exposure to endocrine disruptors in gut microbiota: A systematic review
Laura Calero-Medina, María José Jiménez-Casquet, Leticia Heras-González, Javier Conde-Pipó, Alejandro López-Moro, F. Olea‐Serrano, Miguel Mariscal‐Arcas
Abstract
Endocrine disrupting chemicals (EDCs) can interfere with hormonal actions and have been associated with a higher incidence of metabolic disorders. They affect numerous physiological, biochemical, and endocrinal activities, including reproduction, metabolism, immunity, and behavior. The purpose of this review was to elucidate the association of EDCs in food with the gut microbiota and with metabolic disorders. EDC exposure induces changes that can lead to microbial dysbiosis. Products and by-products released by the microbial metabolism of EDCs can be taken up by the host. Changes in the composition of the microbiota and production of microbial metabolites may have a major impact on the host metabolism.