Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell products
Lindsey Murphy, Russell Marians, Kristen Miller, Matthew Brenton, Rebecca L.V. Mallo, M. Eric Kohler, Terry J. Fry, Amanda Winters
Topics & Concepts
Digital polymerase chain reactionChimeric antigen receptorMultiplexMolecular biologyPolymerase chain reactionComputational biologyReal-time polymerase chain reactionBiologyChemistryImmunotherapyBioinformaticsGeneticsCancerGeneCAR-T cell therapy researchMolecular Biology Techniques and ApplicationsInnovative Microfluidic and Catalytic Techniques Innovation