TIGIT <sup>+</sup> TIM-3 <sup>+</sup> NK cells are correlated with NK cell exhaustion and disease progression in patients with hepatitis B virus‑related hepatocellular carcinoma
Lihua Yu, Xiaoli Liu, Xinhui Wang, Fengna Yan, Peng Wang, Yuyong Jiang, Juan Du, Zhiyun Yang
Abstract
NK cells participate in NK cells function exhaustion and are closely related to the disease progression of patients with HBV-HCC, suggesting a new target for future immunotherapy.
Topics & Concepts
TIGITHepatocellular carcinomaMedicineImmunotherapyHepatitis B virusImmune systemCancer researchImmunologyVirusImmune Cell Function and InteractionGalectins and Cancer BiologyCancer Immunotherapy and Biomarkers