2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation
Xiaodong Sun, Tengjiao Fan, Guohui Sun, Yue Zhou, Yaxin Huang, Na Zhang, Lijiao Zhao, Rugang Zhong, Yongzhen Peng
Topics & Concepts
In vivoGlycolysisApoptosisChemistryReactive oxygen speciesCarmustineCancer researchGlutathioneOxidative stressIn vitroHaCaTPharmacologyIntracellularBiochemistryChemotherapyBiologyMetabolismMedicineInternal medicineEnzymeBiotechnologyEtoposideCancer, Hypoxia, and MetabolismMitochondrial Function and PathologyATP Synthase and ATPases Research