Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions
Ru Huang, Alexander Tamalunas, Raphaela Waidelich, Frank Strittmatter, Christian G. Stief, Martin Hennenberg
Topics & Concepts
MirabegronCarbacholDetrusor muscleMethacholineMuscarinic acetylcholine receptorCholinergicOveractive bladderContraction (grammar)EndocrinologyInternal medicineStimulationChemistryEndothelin 1Muscarinic antagonistMedicineTachyphylaxisUrinary bladderReceptorLungPathologyRespiratory diseaseAlternative medicineUrinary Bladder and Prostate ResearchUrinary Tract Infections ManagementHormonal and reproductive studies