An insight into antimycobacterial and antioxidant potentials of INH-Schiff base complexes and <i>in silico</i> targeting of MtKasB receptor of <i>M. tuberculosis</i>
I. Salim Meeran, Tharsius Raja William Raja, V. N. Azger Dusthakeer, M. Mohamed Naseer Ali, S. Syed Tajudeen, T. K. Shabeer
Abstract
Isoniazid Schiff base complexes synthesized by the molecular hybridization strategy revealed enhanced anti-tubercular (100% killing of M. tb strain) and antioxidant activities.
Topics & Concepts
ChemistryAntimycobacterialIn silicoSchiff baseMycobacterium tuberculosisStereochemistryTuberculosisAntioxidantCombinatorial chemistryBiochemistryPathologyGeneMedicineMetal complexes synthesis and propertiesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds