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Syntheses and Investigations of Conformationally Restricted, Linker-Free α-Amino Acid–BODIPYs via Boron Functionalization

Maodie Wang, Guanyu Zhang, Petia Bobadova‐Parvanova, Kevin M. Smith, M. Graça H. Vicente

2021The Journal of Organic Chemistry16 citationsDOIOpen Access PDF

Abstract

∼ 22 μM), while the spiro-His-BODIPY was the most efficiently internalized, localizing preferentially in the cell lysosomes, ER, and mitochondria.

Topics & Concepts

ChemistryBODIPYAmino acidHistidineLinkerSerineCytotoxicityStereochemistryArginineLysineAspartic acidFluorescenceBiochemistryPhosphorylationComputer scienceQuantum mechanicsPhysicsOperating systemIn vitroLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsPorphyrin and Phthalocyanine Chemistry
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