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Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications

Ana Momčilović, Noortje de Haan, Agnes L. Hipgrave Ederveen, Albert Bondt, Carolien A. M. Koeleman, David Falck, L Neef, Wilma E. Mesker, Rob A.�E.�M. Tollenaar, Arnoud de Ru, Peter A. van Veelen, Manfred Wuhrer, Viktoria Dotz

2020Analytical Chemistry48 citationsDOIOpen Access PDF

Abstract

-glycosylation and age. Furthermore, previously reported associations of IgG Fc glycosylation with age in healthy individuals were confirmed. In conclusion, the new method paves the way for high-throughput multiprotein plasma glycoproteomics.

Topics & Concepts

ChemistryGlycopeptideGlycosylationGlycoproteomicsAntibodyChromatographyImmunoglobulin GImmunoglobulin ABiochemistryImmunologyBiologyAntibioticsGlycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies ResearchGalectins and Cancer Biology
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