2,5-Dimethyl Celecoxib Inhibits Proliferation and Cell Cycle and Induces Apoptosis in Glioblastoma by Suppressing CIP2A/PP2A/Akt Signaling Axis
Dezheng Gao, Alphonce M. K. Nyalali, Yongqiang Hou, Yongxiang Xu, Junlin Zhou, Wenguo Zhao, Bin Huang, Feng Li
Topics & Concepts
Protein kinase BCell cycleApoptosisCell growthCell cycle checkpointChemistryCancer researchProtein phosphatase 2CelecoxibPI3K/AKT/mTOR pathwayCell biologyPhosphorylationBiologyBiochemistryPhosphataseInflammatory mediators and NSAID effectsCancer, Stress, Anesthesia, and Immune ResponseEicosanoids and Hypertension Pharmacology