Copper-Catalyzed <i>Anti</i>-Markovnikov Hydrosilylation of Terminal Alkynes
Zi‐Lu Wang, Feng‐Lian Zhang, Jian‐Lin Xu, Cui‐Cui Shan, Meng Zhao, Yun‐He Xu
Abstract
A copper-catalyzed anti-Markovnikov hydrosilylation of alkynes with PhSiH3 was reported. This reaction represents a notable and efficient example on copper-catalyzed hydrosilylatioin of alkynes, which shows excellent recognition between the terminal and internal triple bonds. Various (hetero)aromatic and aliphatic substituted terminal alkynes underwent this reaction to afford the (E)-vinylsilanes in high yields and with excellent regioselectivity.
Topics & Concepts
Markovnikov's ruleHydrosilylationChemistryRegioselectivityCatalysisTerminal (telecommunication)CopperCombinatorial chemistryOrganic chemistryMedicinal chemistryPolymer chemistryTelecommunicationsComputer scienceOrganoboron and organosilicon chemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions