Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases
Carlo Condello, David Westaway, Stanley B. Prusiner
Abstract
This Viewpoint describes the evidence for iatrogenic disease based on amyloid-β prions and the possibility that Alzheimer disease has an iatrogenic form wherein amyloid β and tau behave as prions that transmit the disease.
Topics & Concepts
DiseaseAmyloid (mycology)NeuroscienceAmyloid βAlzheimer's diseaseMedicinePathologyPsychologyPrion Diseases and Protein MisfoldingAlzheimer's disease research and treatmentsNeurological diseases and metabolism