Synthesis, pharmacological evaluation, and modeling of novel quaternary ammonium salts derived from β-carboline containing an imidazole moiety as angiogenesis inhibitors
Shuang Chen, Xiaofei Chen, Dongping Qiu, Jiahao Wei, Jie Zhang, Liang Guo
Topics & Concepts
ChemistryMoietyImidazoleAngiogenesisCombinatorial chemistryAmmoniumStereochemistryChemical synthesisMolecular modelStructure–activity relationshipBiochemistryIn vitroOrganic chemistryInternal medicineMedicineSynthesis and bioactivity of alkaloidsMulticomponent Synthesis of HeterocyclesSynthesis and Biological Evaluation