Rh<sub>2</sub>(<scp>ii</scp>)-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor–donor carbenes
Dong Zhu, Tongxiang Cao, Kai Chen, Shifa Zhu
Abstract
The chiral dirhodium( ii ) tetracarboxylate-catalyzed enantioselective intramolecular Büchner reaction and aromatic substitution of donor/donor-carbenes were reported and a series of valuable chiral polycyclic products were synthesized.
Topics & Concepts
Enantioselective synthesisChemistryCarbeneIntramolecular forceDiazoSubstituentFluoreneMedicinal chemistryCatalysisRacemizationStereochemistryOrganic chemistryPolymerCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsAsymmetric Synthesis and Catalysis