A review of the potential therapeutic and cosmetic use of propolis in topical formulations
Mônica Valero da Silva, Nélio Gomes De Moura, Andréa Barretto Motoyama, Vânia Maria Moraes Ferreira, A Abu-Mellal, N Koolaji, R Duke, V Tran, C Duke, M Afkhamizadeh, R Aboutorabi, H Ravari, Fathi Najafi, M, Ataei Azimi, S, Javadian Langaroodi, A Yaghoubi, M Sahebkar, A, M Ahn, S Kumazawa, T Hamasaka, K Bang, T Nakayama, M Ahn, S Kumazawa, Y Usui, J Nakamura, M Matsuka, F Zhu, T Nakayama, A Akca, G Akca, F Topu, E Macit, L Pikdken, I zgen, G Aliev, M Obrenovich, V Reddy, J Shenk, P Moreira, A Nunomura, X Zhu, M Smith, G Perry, N Baltas, O Yildiz, S Kolayli, V Bankova, M Popova, B Trusheva, V Bankova, G Boudourova-Krasteva, J Sforcin, X Frete, A Kujumgiev, R Maimoni-Rodella, S Popov, V Barbosa, Gfc Scheiffer, Agl Cardozo, E Pietruchinski, C Santos, D Silveira, Arp Bertocco, S Bennett, M Grant, S Aldred, N Bhat, S Bapat, K Asawa, M Tak, P Chaturvedi, V Gupta, P George, S Boisard, Le Ray, A Landreau, A Kempf, M Cassisa, V Flurin, C Richomme, P, Y Boufadi, J Soubhye, A Riazi, A Rousseau, M Vanhaeverbeek, J Nve, K Boudjeltia, P Van Antwerpen, W Bretz, N Paulino, J Nr, A Moreira, M Butnariu, C Giuchici, Cairo Do Amaral
Abstract
A good deal of research has been carried out on the establishment and characterization of antioxidants and antibacterial products from natural sources for topical use. Recently, investors mainly from the cosmetics industry have become interested in products from different species, not only for their individual active principles but also in the crude extract itself. Propolis is one of such products. Several previous reports have demonstrated the antimicrobial, antiinflammatory, and wound healing effects of propolis. Additionally, what has drawn attention of the pharmaceutical industry to propolis and its derivatives, such as throat spray, is related to its antioxidant properties, having the potential for treatment and prevention of oxidative stress-mediated diseases, such as those developed on the skin, as well as aging. This literature review will focus on propolis composition and related potential uses in topical pharmaceutical and cosmetic formulations.