CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells
Camilla Wilk, Laura Effenberg, Hanna Abberger, Laura Steenpaß, Wiebke Hansen, Michael Zeschnigk, Carsten J. Kirschning, Jan Buer, Jan Kehrmann
Topics & Concepts
Jurkat cellsDemethylationCas9DNA methylationMethylationBiologyFOXP3TransfectionMolecular biologyDNA demethylationEpigeneticsCell biologyT cellCRISPRGeneticsGeneGene expressionImmune systemImmune Cell Function and InteractionT-cell and B-cell ImmunologyCRISPR and Genetic Engineering