Aging induces cell loss and a decline in phagosome processing in the mouse retinal pigment epithelium
Jessica Y.W., Ursula Greferath, Josephine H. C. Wong, Linda J. Fothergill, Andrew I. Jobling, Kirstan A. Vessey, Erica L. Fletcher
Topics & Concepts
Retinal pigment epitheliumPhagosomeMacular degenerationCell biologyRetinaBiologyRetinalPhagocytosisLipofuscinTranscriptomeLysosomeAutophagyDownregulation and upregulationRetinal degenerationSenescenceGene expressionMedicineGeneOphthalmologyNeuroscienceGeneticsApoptosisBiochemistryEnzymeRetinal Diseases and TreatmentsRetinal Development and DisordersBarrier Structure and Function Studies