Litcius/Paper detail

Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors

Qiuping Xiang, Guolong Luo, Cheng Zhang, Qingqing Hu, Chao Wang, Tianbang Wu, Hongrui Xu, Jiankang Hu, Xiaoxi Zhuang, Maofeng Zhang, Shuang Wu, Jinxin Xu, Yan Zhang, Jinsong Liu, Yong Xu

2022European Journal of Medicinal Chemistry19 citationsDOIOpen Access PDF

Topics & Concepts

BromodomainChemistryEpigeneticsCancer researchPharmacologyComputational biologyBiochemistryBiologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments