Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy
Takahiro Yamazaki, Alexander Kirchmair, Ai Sato, Aitziber Buqué, Marissa Rybstein, Giulia Petroni, Norma Bloy, Francesca Finotello, Lena Stafford, Esther Navarro Manzano, Francisco Ayala, Elena García-Martínez, Silvia C. Formenti, Zlatko Trajanoski, Lorenzo Galluzzi
Topics & Concepts
AutophagyBiologyProgrammed cell deathCancer researchCell biologyImmunogenic cell deathMitochondrionDNA damageGene knockdownBystander effectImmune systemImmunityApoptosisImmunologyImmunotherapyDNAGeneticsAutophagy in Disease and Therapyinterferon and immune responsesCancer-related molecular mechanisms research