Preparation of hexafluoroisopropyl esters by oxidative esterification of aldehydes using sodium persulfate
Arturo León Sandoval, Fabrizio Politano, Mason L. Witko, Nicholas E. Leadbeater
Abstract
A simple, metal-free route for the oxidative esterification of aldehydes to yield hexafluoroisopropyl esters is reported. The methodology employs sodium persulfate and a catalytic quantity of a nitroxide and is applicable to aromatic, heteroaromatic, and aliphatic aldehydes.
Topics & Concepts
ChemistryPersulfateOxidative phosphorylationOrganic chemistrySodiumSodium persulfateCombinatorial chemistryBiochemistryCatalysisOxidative Organic Chemistry ReactionsChemical Synthesis and ReactionsSulfur-Based Synthesis Techniques