Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons
Santosh Pothula, Rong-Jian Liu, Min Wu, Alexa‐Nicole Sliby, Marina R. Picciotto, Pradeep Banerjee, Ronald S. Duman
Topics & Concepts
Excitatory postsynaptic potentialNeuroscienceNMDA receptorPrefrontal cortexAntidepressantInhibitory postsynaptic potentialGlutamatergicSynaptic plasticityBiologyGlutamate receptorHippocampusReceptorMedicineInternal medicineCognitionTreatment of Major DepressionNeuroscience and Neuropharmacology ResearchTryptophan and brain disorders