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Wnt–β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression

Jasmin Quandt, Stephen Arnovitz, Leila Haghi, Janine Woehlk, Azam Mohsin, Michael K. Okoreeh, Priya Mathur, Akinola Olumide Emmanuel, Abu Osman, Manisha Krishnan, Samuel B. Morin, Alexander T. Pearson, Randy F. Sweis, Joel Pekow, Christopher R. Weber, Khashayarsha Khazaie, Fotini Gounari

2021Nature Immunology90 citationsDOIOpen Access PDF

Topics & Concepts

Wnt signaling pathwayInflammatory bowel diseaseFOXP3ImmunologyEpigeneticsBiologyCancer researchRAR-related orphan receptor gammaCateninInflammationProinflammatory cytokineSignal transductionCell biologyMedicineDiseaseGeneGeneticsInternal medicineImmune systemT-cell and B-cell ImmunologyImmune Cell Function and InteractionIL-33, ST2, and ILC Pathways
Wnt–β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression | Litcius