Synthetic Cells Extract Semantic Information From Their Environment
Beatrice Ruzzante, Lorenzo Del Moro, Maurizio Magarini, Pasquale Stano
2023IEEE Transactions on Molecular Biological and Multi-Scale Communications19 citationsDOIOpen Access PDF
Abstract
Based on a recently reported operative definition of semantic information, due to Kolchinsky and Wolpert (2018), here we present a research program based on the intersection between synthetic biology, molecular communication, and information theory. In particular, we first describe and emphasize the role of “synthetic cells” as new (bio)technological platform for theoretical and applied investigations; next we simulate a smart drug delivery scenario whereby synthetic cells extract semantic information from their environment (made of cancerous cells, which provide a signal molecule that triggers the production of a cytotoxic drug by the synthetic cell).
Topics & Concepts
Intersection (aeronautics)Synthetic biologyComputer scienceSynthetic dataData scienceArtificial intelligenceCognitive scienceComputational biologyBiologyEngineeringPsychologyAerospace engineeringMolecular Communication and NanonetworksGene Regulatory Network AnalysisAdvanced biosensing and bioanalysis techniques