Evaluation of the Performance and Clinical Impact of a Rapid Phenotypic Susceptibility Testing Method Directly from Positive Blood Culture at a Pediatric Hospital
Thao Truong, Kanokporn Mongkolrattanothai, Irvin Ibarra Flores, Jennifer Dien Bard
Abstract
Bloodstream infection poses a significant medical emergency that necessitates timely administration of appropriate antibiotics. Standard laboratory workup for antimicrobial susceptibility testing (AST) involves subculture of organisms from positive blood bottles followed by testing using broth microdilution; however, this process can take several days.
Topics & Concepts
Blood cultureAntibioticsBroth microdilutionMedicineSubculture (biology)Clinical microbiologyBacteremiaIntensive care medicineMicrobiologyBiologyMinimum inhibitory concentrationBacterial Identification and Susceptibility TestingStreptococcal Infections and TreatmentsAntimicrobial Resistance in Staphylococcus