Genetic Variants of the DSF Quorum Sensing System in Stenotrophomonas maltophilia Influence Virulence and Resistance Phenotypes Among Genotypically Diverse Clinical Isolates
Daniel Yero, Pol Huedo, Oscar Conchillo‐Solé, Sònia Martínez-Servat, Uwe Mamat, Xavier Coves, Ferran Llanas, Ignasi Roca, Jordi Vilà, Ulrich E. Schaible, Xavier Daura, Isidre Gibert
Abstract
related to the synthesis of an alternative Flp/Tad pilus. Overall, this study establishes a link between the DSF-based QS system and the virulence and resistance phenotypes in this species, and identifies potential high-risk clones circulating in European hospitals.
Topics & Concepts
VirulenceStenotrophomonas maltophiliaBiologyQuorum sensingMicrobiologyGalleria mellonellaTicarcillinGenotypeGeneticsPhenotypeMultilocus sequence typingStenotrophomonasGenePseudomonas aeruginosaAntibiotic resistanceBacteriaAntibioticsPseudomonasImipenemInfections and bacterial resistanceBacterial biofilms and quorum sensingPlant Pathogenic Bacteria Studies