Morin ameliorates methotrexate-induced hepatotoxicity via targeting Nrf2/HO-1 and Bax/Bcl2/Caspase-3 signaling pathways
Hamit Emre Kızıl, Cüneyt Çağlayan, Ekrem Darendelioğlu, Adnan Ayna, Cihan Gür, Fatih Mehmet Kandemır, Sefa Küçükler
Topics & Concepts
Oxidative stressPharmacologyMorinSuperoxide dismutaseGlutathioneApoptosisChemistryGlutathione peroxidaseLiver injuryCaspase 3MedicineBiochemistryProgrammed cell deathEnzymePathologyChemotherapy-induced organ toxicity mitigationDrug-Induced Hepatotoxicity and ProtectionAcute Lymphoblastic Leukemia research