Electrochemical Tandem Cyclization of Unsaturated Oximes with Diselenides: A General Approach to Seleno Isoxazolines Derivatives with Quaternary Carbon Center
Wenchao Gao, Beibei Li, Luyi Zong, Lintao Yu, Xuyang Li, Qiyang Li, Xu Zhang, Sheng Zhang, Kun Xu
Abstract
Abstract Electrochemical oxidative tandem cyclization of unsaturated oximes with diselenides has been developed to provide a general access to seleno isoxazolines containing a quaternary carbon center (35 examples). This novel protocol features with mild reaction conditions (metal‐ and oxidant‐free), good functional group tolerance and promising scalability. Moreover, plausible reaction pathways have been proposed.
Topics & Concepts
ChemistryTandemQuaternary carbonElectrochemistryFunctional groupCombinatorial chemistryCarbon fibersOrganic chemistryCatalysisEnantioselective synthesisElectrodeComposite materialComposite numberPhysical chemistryMaterials sciencePolymerSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods