TRIM59 guards ER proteostasis and prevents Bortezomib-mediated colorectal cancer (CRC) cells’ killing
Xuejia Feng, Gui Yang, Litian Zhang, Shishi Tao, Joong Sup Shim, Liang Chen, Qingxia Wu
Topics & Concepts
ProteostasisUnfolded protein responseEndoplasmic reticulumEndoplasmic-reticulum-associated protein degradationBortezomibBiologyCancer researchCell biologyGene knockdownTunicamycinMG132ApoptosisProteasome inhibitorProteasomeImmunologyBiochemistryMultiple myelomainterferon and immune responsesEndoplasmic Reticulum Stress and DiseaseCancer Mechanisms and Therapy