Alleviation of DSS-induced colitis<i>via Lactobacillus acidophilus</i>treatment in mice
Woon-Ki Kim, Dae Hee Han, You Jin Jang, Sungjun Park, Sung Jae Jang, Giljae Lee, Hyuk Seung Han, GwangPyo Ko
Abstract
, respectively) (P < 0.05). Our study suggests that L. acidophilus KBL402 and KBL409 could be useful for the prevention or treatment of IBDs in various ways including the modulation of immune responses and miR expression, restoration of the gut microbiota, and production of metabolites.
Topics & Concepts
Lactobacillus acidophilusColitisImmune systemUlcerative colitisMedicineImmunologyBiologyBacteriaProbioticInternal medicineDiseaseGeneticsGut microbiota and healthProbiotics and Fermented FoodsClostridium difficile and Clostridium perfringens research