Force-dependent trans-endocytosis by breast cancer cells depletes costimulatory receptor CD80 and attenuates T cell activation
Seungman Park, Yu Shi, Byoung Choul Kim, Myung Hyun Jo, Leilani O. Cruz, Zheming Gou, Taekjip Ha, Li‐Fan Lu, Daniel H. Reich, Yun Chen
Topics & Concepts
CD80EndocytosisAntigen-presenting cellCytotoxic T cellChemistryCancer cellT cellCell biologyCD86Cancer researchReceptorCancerImmunologyImmune systemBiologyMedicineCD40Internal medicineBiochemistryIn vitroImmunotherapy and Immune ResponsesCell Adhesion Molecules ResearchCellular Mechanics and Interactions