Design, synthesis and biological profiling of bis-thiazole linked Schiff bases as effective enzyme inhibitors for targeting urease and thymidine phosphorylase proteins
Yousaf Khan, Hina Sarfraz, Mahrukh Naseem, Rubina Adnan, Syeda Farwa Naqvi, Azmatullah Khan, Urooba Gulshan, Syed Aminullah
Topics & Concepts
Thymidine phosphorylaseEnzymeBiochemistryChemistryUreaseThymidineDocking (animal)Active siteGlycogen phosphorylaseThioureaNucleotide salvageBiologyStructure–activity relationshipEnzyme inhibitorBiological activityBinding siteMicrobial Applications in Construction MaterialsEnzyme Production and CharacterizationSynthesis and Characterization of Heterocyclic Compounds