Litcius/Paper detail

A comparison of two pulp revascularization techniques using platelet-rich plasma and whole blood clot

Naren Ramachandran, Shishir Singh, Rajesh Podar, Gaurav Kulkarni, Roshan Shetty, Padmini Chandrasekhar

2020Journal of Conservative Dentistry38 citationsDOIOpen Access PDF

Abstract

<b>Aim:</b> The aim of this preliminary study was to compare outcomes of two regenerative endodontic protocols in necrotic teeth with open apices.<br><b>Methodology:</b> Forty teeth with open apices in patients with an age range of 15-54 were randomly distributed in two groups: group 1, with whole blood clot in the canal (n=20) and group 2, whole blood with Platelet rich plasma (PRP) in the canal (n=20). Clinical and radiological follow up assessments were undertaken over a period ranging from 6 months to one year. Radiographic Root Area (RRA) was measured using the freeware ImageJ. Statistical analysis was performed using the independent samples t test and the Chi-squared test, the significance level was set at p=0.05. <br><b>Results:</b> There was no difference in the percentage change in RRA between the PRP group and whole blood-clot + PRP group.<br><b>Conclusion:</b> Whole blood clot and PRP are comparable on the grounds of percentage change in RRA and there is no statistically significant difference between the two in a follow-up period of up to one year.<br>

Topics & Concepts

MedicinePlatelet-rich plasmaDentistryWhole bloodRoot canalRevascularizationStatistical significanceSignificant differencePlateletPulp (tooth)SurgeryInternal medicineMyocardial infarctionEndodontics and Root Canal TreatmentsPeriodontal Regeneration and TreatmentsDental Trauma and Treatments