Linezolid-Resistant Enterococcus faecalis of Chicken Origin Harbored Chromosome-Borne <i>optrA</i> and Plasmid-Borne <i>cfr</i> , <i>cfr</i> (D), and <i>poxtA2</i> Genes
Biao Tang, Chenhui Zou, Štefan Schwarz, Chunyan Xu, Wenbo Hao, Xiaomei Yan, Yuting Huang, Juan Ni, Hua Yang, Xiang‐Dang Du, Xinxin Shan
Abstract
In this study, the simultaneous occurrence of four acquired oxazolidinone resistance genes [ optrA , cfr , cfr (D), and poxtA2 ] was identified in an E. faecalis isolate of chicken origin. The association of the cfr gene with a novel pseudocompound transposon Tn 7515 integrated into a pCF10-like pheromone-responsive conjugative plasmid will accelerate its dissemination.
Topics & Concepts
PlasmidEnterococcus faecalisBiologyTransposable elementGeneGeneticsChromosomeLinezolidGenomeBacteriaStaphylococcus aureusVancomycinEscherichia coliAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingAntibiotic Resistance in Bacteria