A multifunctional chitosan based porous membrane for pH-responsive antibacterial activity and promotion of infected wound healing
Shan Pu, Jiale Zhang, Chaoting Shi, Xiandeng Hou, Ka Li, Jinhua Feng, Lan Wu
Abstract
observation and histological evaluation demonstrated that CHZ-10 could not only effectively inhibit bacterial infection and reduce inflammation of the wound, but also promote its re-epithelialization, granulation, tissue formation and collagen fibre growth, leading to effectively enhanced wound-healing. This work provides a new method for the easy construction of multifunctional antibacterial dressings based on CS, showing promise for application in clinical wound care.
Topics & Concepts
ChitosanWound healingMaterials scienceAntibacterial activityMembranePromotion (chess)PorosityChemical engineeringChemistryComposite materialMedicineBacteriaBiochemistrySurgeryEngineeringBiologyGeneticsPoliticsPolitical scienceLawWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsNanocomposite Films for Food Packaging