Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)—A European Society of Organ Transplantation (ESOT) Consensus Statement
Marco Carbone, Andrea Della Penna, Chiara Mazzarelli, Eléonora De Martin, Christina Villard, Annika Bergquist, Pål‐Dag Line, James Neuberger, Sarah Al-Shakhshir, Palak Trivedi, Ulrich Baumann, Laura Cristoferi, Johannes R. Hov, Björn Fischler, N. H. Hadzic, Dominique Debray, Lorenzo D’Antiga, Nazia Selzner, L Belli, Silvio Nadalin
Abstract
Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD) and a lead indication for liver transplantation (LT) in the western world. In this article, we present a Consensus Statement on LT practice, developed by a dedicated Guidelines' Taskforce of the European Society of Organ Transplantation (ESOT). The overarching goal is to provide practical guidance on commonly debated topics, including indications and timing of LT, management of bile duct stenosis in patients on the transplant waiting list, technical aspects of transplantation, immunosuppressive strategies post-transplant, timing and extension of intestinal resection and futility criteria for re-transplantation.