Genomic Insights into Methicillin-Resistant Staphylococcus aureus <i>spa</i> Type t899 Isolates Belonging to Different Sequence Types
Henok Ayalew Tegegne, Ivana Koláčková, Martina Florianová, Pierre Wattiau, Tereza Gelbíčová, Cécile Boland, Jean-Yves Madec, Marisa Haenni, Renáta Karpíšková
Abstract
This study showed the genetic diversity and population structure of S. aureus presenting the same spa type, t899, but belonging to different STs. Our findings revealed that these isolates vary deeply in their core and accessory genomes, contrary to what is regularly inferred from studies using spa typing only.
Topics & Concepts
BiologyStaphylococcus aureusGenomeTypingGeneticsGenetic diversityType (biology)PopulationMicrobiologyEvolutionary biologyGeneMedicineBacteriaEcologyEnvironmental healthAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingBiochemical and Structural Characterization