Litcius/Paper detail

Proceedings of the 27th European Paediatric Rheumatology Congress (PReS 2021)

Augūnaitė, Laura, Jakinevičiūtė, Miglė, Šnipaitienė, Aušra, Jankauskaitė, Lina

2021Pediatric Rheumatology25 citationsDOIOpen Access PDF

Abstract

flares.Eleven serious infections were reported in nine patients (pneumonia (n=3), one each: anal abscess, appendicitis, bronchitis, herpes virus infection, influenza, orchitis, pyelonephritis and tonsillitis).Conclusion: Canakinumab proved effective to control disease activity and prevent flares in MKD during the 72-week study period.Individual dose adjustments may be required to maintain the therapeutic effect of canakinumab.No new or unexpected safety concerns were reported.

Topics & Concepts

MedicineRheumatologyInternal medicineFamily medicineAutoimmune and Inflammatory Disorders ResearchInflammasome and immune disordersPediatric health and respiratory diseases