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Niemann Pick C2 protein enables cholesterol transfer from endo-lysosomes to the plasma membrane for efflux by shedding of extracellular vesicles

Alice Dupont Juhl, Frederik W. Lund, Maria Jensen, Maria Szomek, Christian W. Heegaard, Peter Guttmann, Stephan Werner, James G. McNally, Gerd Schneider, Sergey Kapishnikov, Daniel Wüstner

2021Chemistry and Physics of Lipids35 citationsDOI

Topics & Concepts

ChemistryVesicleEffluxExtracellularMembraneExtracellular vesiclesCholesterolBiophysicsCell biologyBiochemistryBiologyLysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolismAdenosine and Purinergic Signaling
Niemann Pick C2 protein enables cholesterol transfer from endo-lysosomes to the plasma membrane for efflux by shedding of extracellular vesicles | Litcius