Effect of pH modifiers on the solubility, dissolution rate, and stability of telmisartan solid dispersions produced by hot-melt extrusion technology
Ahmed Almotairy, Mashan Almutairi, Abdulmajeed Althobaiti, Mohammed Alyahya, Sandeep Sarabu, Abdullah Alzahrani, Feng Zhang, Suresh Bandari, Michael A. Repka
Topics & Concepts
TelmisartanDifferential scanning calorimetrySolubilityDissolutionExtrusionMaterials scienceAmorphous solidRecrystallization (geology)Fourier transform infrared spectroscopyChemical engineeringNuclear chemistryChemistryChromatographyOrganic chemistryMetallurgyPaleontologyThermodynamicsMedicineEngineeringPhysicsRadiologyBlood pressureBiologyDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesAnalytical Methods in Pharmaceuticals