Four ionones and ionone glycosides from the whole plant of <i>Rehmannia piasezkii</i>
Jie Zhou, Guo-Ru Shi, Wanqi Zhang, Ruo-Yun Chen, Yanfei Liu, De‐Quan Yu
Abstract
Four new ionones and ionone glycosides (1–4) were isolated from the whole plant of Rehmannia piasezkii Maxim. Their planar structures as well as absolute configuration were confirmed via spectroscopic analysis, ECD calculation, and X-ray crystallography. Compounds 1–4 were tested for their cytotoxicity against five human tumor cell lines and ability to inhibit LPS-activated NO production in the BV2 cell line.
Topics & Concepts
IononeGlycosideTraditional medicineChemistryTerpenoidTriterpeneStereochemistryMedicineAlternative medicinePathologyPhytochemistry and Biological ActivitiesNatural product bioactivities and synthesisPhytochemistry and Bioactive Compounds