Chronic Oxaliplatin Treatment Induces CIPN in Mice via Activation of the TXNIP Pathway
Junwei Du, Leland C. Sudlow, Kiana Shahverdi, Haiying Zhou, Carla M. Yuede, Lara W. Crock, Daniel A. Hunter, Judith P. Golden, Shamim Mollah, Matthew D. Wood, Mikhail Y. Berezin
Topics & Concepts
TXNIPOxaliplatinMedicinePeripheral neuropathySciatic nerveThioredoxin-Interacting ProteinNeurotoxicityNeuropathic painPharmacologyOxidative stressDownregulation and upregulationChronic painInflammationAnesthesiaNeuroprotectionSide effect (computer science)NeurologyPathogenesisCancer researchIntraperitoneal injectionPathologyInternal medicineBioinformaticsPeripheralPathophysiologyDorsal root ganglionCancer Treatment and PharmacologyColorectal Cancer Treatments and StudiesSilymarin and Mushroom Poisoning